Sestola is easily reachable from Modena through the SP4 – Fondovalle (Vignola, Marano, Fanano, Sestola) or along the SS12 – Nuova Estense up to Pavullo and then the SP30 (Renno, Castellaro, Sestola).

Those coming instead from the Tuscan side can opt for the SS12 and then the SS324 (Abetone, Fiumalbo, Pievepelago, Montecreto, Sestola) or for the SS64 and the SS324 (Porretta Terme, Silla, Lizzano in Belvedere, Fanano, Sestola).